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Lipoprotein Fractionation Ion Mobility: A Revolutionary Technique for Cardiovascular Disease Diagnosis

Introduction

Cardiovascular disease (CVD) is a leading cause of death worldwide. Early diagnosis and treatment are crucial in preventing its progression. Lipoprotein fractionation ion mobility (LFIM) is a novel technique that has shown promising results in identifying individuals at high risk of CVD. In this article, we will discuss LFIM and its potential as a diagnostic tool for CVD.

What is Lipoprotein Fractionation Ion Mobility?

LFIM is a technique that separates lipoproteins based on their size and charge using ion mobility spectrometry. Lipoproteins are particles that transport lipids, such as cholesterol and triglycerides, in the blood. There are different types of lipoproteins, including low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very-low-density lipoprotein (VLDL). LDL is often referred to as “bad” cholesterol, while HDL is known as “good” cholesterol.

LFIM separates lipoproteins into subclasses based on their size and charge. This allows for a more detailed analysis of lipoprotein profiles, which can provide valuable information about an individual’s risk of CVD. For example, individuals with a high concentration of small, dense LDL particles are at a higher risk of CVD than those with a lower concentration of these particles.

LFIM as a Diagnostic Tool for CVD

LFIM has shown promising results in identifying individuals at high risk of CVD. A study published in the Journal of the American College of Cardiology found that LFIM was able to identify individuals with a higher risk of CVD than traditional lipid tests. The study also found that LFIM was able to identify individuals with a higher risk of CVD who had normal levels of traditional lipid markers.

LFIM has also been shown to be useful in monitoring the effectiveness of lipid-lowering therapies. A study published in the Journal of Clinical Lipidology found that LFIM was able to detect changes in lipoprotein profiles in response to lipid-lowering therapies that were not detected by traditional lipid tests.

Conclusion

LFIM is a revolutionary technique that has shown promising results in identifying individuals at high risk of CVD. Its ability to provide detailed lipoprotein profiles makes it a valuable diagnostic tool for CVD. LFIM has the potential to improve the accuracy of CVD diagnosis and monitoring, leading to better outcomes for patients. As research in this area continues, LFIM may become a standard tool in the diagnosis and management of CVD.

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10 lipoprotein fractionation ion mobility for reference

1.Cardio IQ® Lipoprotein Fractionation Ion Mobility – Quest Diagnostics

  • Author: Cardio
  • Publish: 18 days ago
  • Rating: 4star(1694 Rating)
  • Highest rating: 5star
  • Lowest rating: 1star
  • Descriptions: Ion mobility lipoprotein fractionation is a technology that uses gas-phase (laminar flow) electrophoresis to separate unmodified lipoproteins on the basis of …
  • More : Ion mobility lipoprotein fractionation is a technology that uses gas-phase (laminar flow) electrophoresis to separate unmodified lipoproteins on the basis of …
  • Source : https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq134

2.Lipoprotein Fractionation, Ion Mobility – Cleveland HeartLab, Inc.

  • Author: Lipoprotein
  • Publish: 1 days ago
  • Rating: 1star(553 Rating)
  • Highest rating: 3star
  • Lowest rating: 3star
  • Descriptions:
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  • Source : https://www.clevelandheartlab.com/tests/lipoprotein-fractionation-ion-mobility/

3.Lipid Panel with Lipoprotein Fractionation, Ion Mobility

  • Author: Lipid
  • Publish: 21 days ago
  • Rating: 4star(1206 Rating)
  • Highest rating: 4star
  • Lowest rating: 1star
  • Descriptions: Lipid Subfractionation by Ion Mobility separates, counts, and measures the particles that make up LDL-C and HDL-C, providing an indication of future …
  • More : Lipid Subfractionation by Ion Mobility separates, counts, and measures the particles that make up LDL-C and HDL-C, providing an indication of future …
  • Source : https://www.sonoraquest.com/patient/knowledge-center/lipid-panel-with-lipoprotein-fractionation-ion-mobility/

4.[PDF] Cardio IQ™ Ion Mobility – Sonora Quest Laboratories

  • Author: [PDF]
  • Publish: 10 days ago
  • Rating: 3star(654 Rating)
  • Highest rating: 4star
  • Lowest rating: 2star
  • Descriptions: Figure 1. Cardio IQ Ion Mobility separation of lipoprotein. Ionized lipoproteins migrate across a laminar gas-phase flow based on size and electrical field.
  • More : Figure 1. Cardio IQ Ion Mobility separation of lipoprotein. Ionized lipoproteins migrate across a laminar gas-phase flow based on size and electrical field.
  • Source : https://providers.sonoraquest.com/media/1106/cardioiq_ionmobility_1014_web-3.pdf

5.Ion Mobility Lipoprotein Subfractionation: Further Beyond Cholesterol

  • Author: Ion
  • Publish: 7 days ago
  • Rating: 4star(1535 Rating)
  • Highest rating: 5star
  • Lowest rating: 2star
  • Descriptions:
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  • Source : https://www.optimaldx.com/research-blog/ion-mobility-lipoprotein-subfractionation-further-beyond-cholesterol

6.Association of particles of lipoprotein subclasses with arterial …

  • Author: Association
  • Publish: 7 days ago
  • Rating: 2star(453 Rating)
  • Highest rating: 5star
  • Lowest rating: 1star
  • Descriptions:
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  • Source : https://tehj.springeropen.com/articles/10.1186/s43044-020-00046-4

7.Lipoprotein Sub-Fractions by Ion-Mobility Analysis and Its … – PubMed

  • Author: Lipoprotein
  • Publish: 17 days ago
  • Rating: 3star(1752 Rating)
  • Highest rating: 4star
  • Lowest rating: 1star
  • Descriptions:
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  • Source : https://pubmed.ncbi.nlm.nih.gov/30224606/

8.ION MOBILITY ANALYSIS OF LIPOPROTEIN SUBFRACTIONS …

  • Author: ION
  • Publish: 5 days ago
  • Rating: 1star(785 Rating)
  • Highest rating: 5star
  • Lowest rating: 3star
  • Descriptions:
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  • Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772123/

9.Cardio IQ™ Lipoprotein Fractionation, Ion Mobility – Ulta Lab Tests

  • Author: Cardio
  • Publish: 29 days ago
  • Rating: 2star(502 Rating)
  • Highest rating: 5star
  • Lowest rating: 3star
  • Descriptions: Description: Ion Mobility Lipoprotein Fractionation is a test that uses a gas-phase technology to separate the lipid particles by size. As each particle is …
  • More : Description: Ion Mobility Lipoprotein Fractionation is a test that uses a gas-phase technology to separate the lipid particles by size. As each particle is …
  • Source : https://www.ultalabtests.com/test/cardio-iq-lipoprotein-fractionation-ion-mobility

10.Is advanced lipoprotein testing useful? – Harvard Health

  • Author: Is
  • Publish: 20 days ago
  • Rating: 4star(719 Rating)
  • Highest rating: 3star
  • Lowest rating: 3star
  • Descriptions:
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  • Source : https://www.health.harvard.edu/cholesterol/is-advanced-lipoprotein-testing-useful

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