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How Does Acetazolamide Cause Anemia? – A Comprehensive Guide




How Does Acetazolamide Cause Anemia? – A Comprehensive Guide

Introduction

Acetazolamide is a medication that is commonly used to treat glaucoma, altitude sickness, and epilepsy. However, like all medications, it can have side effects. One of the potential side effects of acetazolamide is anemia. In this article, we will explore how acetazolamide can cause anemia and what you can do to prevent it.

What is Acetazolamide?

Acetazolamide is a carbonic anhydrase inhibitor. It works by reducing the amount of bicarbonate in the body, which can help to reduce pressure in the eyes and prevent altitude sickness. It is also used to treat epilepsy and some types of edema.

How Does Acetazolamide Cause Anemia?

Acetazolamide can cause anemia by reducing the production of red blood cells. Red blood cells are responsible for carrying oxygen throughout the body. When the body does not produce enough red blood cells, it can lead to anemia.

Acetazolamide can also cause anemia by reducing the amount of iron in the body. Iron is an essential mineral that is needed to produce red blood cells. When the body does not have enough iron, it can lead to anemia.

Finally, acetazolamide can cause anemia by increasing the breakdown of red blood cells. This can happen because acetazolamide can cause the blood to become more acidic, which can damage red blood cells and cause them to break down more quickly.

Symptoms of Anemia

The symptoms of anemia can vary depending on the severity of the condition. Some common symptoms of anemia include:

  • Fatigue
  • Weakness
  • Dizziness
  • Shortness of breath
  • Pale skin
  • Chest pain
  • Irregular heartbeat

If you are experiencing any of these symptoms while taking acetazolamide, you should contact your doctor immediately.

Preventing Anemia

If you are taking acetazolamide, there are several things you can do to prevent anemia:

  • Make sure you are getting enough iron in your diet. Good sources of iron include red meat, poultry, fish, beans, and leafy green vegetables.
  • Take an iron supplement if your doctor recommends it.
  • Get regular blood tests to monitor your red blood cell count.
  • If you are experiencing symptoms of anemia, contact your doctor immediately.

Conclusion

Acetazolamide is a medication that can be very helpful in treating certain conditions. However, it can also have side effects, including anemia. If you are taking acetazolamide, it is important to be aware of the potential for anemia and to take steps to prevent it. If you are experiencing symptoms of anemia, contact your doctor immediately.

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1.Acetazolamide-associated aplastic anaemia – PubMed

  • Publish: 27 days ago
  • Rating: 4star(1949 Rating)
  • Highest rating: 3star
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  • Descriptions: The results strongly indicate that acetazolamide treatment is associated with a substantial increase in the risk of developing aplastic anaemia. MeSH terms.
  • Source : https://pubmed.ncbi.nlm.nih.gov/2280240/

2.Acetazolamide – an overview | ScienceDirect Topics

  • Publish: 17 days ago
  • Rating: 2star(355 Rating)
  • Highest rating: 3star
  • Lowest rating: 2star
  • Descriptions: These findings suggest that acetazolamide is associated with a substantially increased risk of aplastic anemia. However, the National Registry of Drug-Induced …
  • Source : https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/acetazolamide

3.Acetazolamide-Induced Thrombocytopenia | Coagulation Disorders

  • Publish: 10 days ago
  • Rating: 4star(1810 Rating)
  • Highest rating: 4star
  • Lowest rating: 2star
  • Descriptions: Acetazolamide-associatedthrombocytopenia was previously described as part of aplastic anemia or otherorgan involvement; however, evidence that the drug may …
  • Source : https://jamanetwork.com/journals/jamaophthalmology/fullarticle/416588

4.Diamox (acetazolamide) side effects

  • Publish: 24 days ago
  • Rating: 1star(1167 Rating)
  • Highest rating: 5star
  • Lowest rating: 3star
  • Descriptions:
  • Source : https://webeye.ophth.uiowa.edu/eyeforum/article/iih/diamox.htm

5.Acetazolamide‐associated aplastic anaemia – Wiley Online Library

  • Publish: 4 days ago
  • Rating: 5star(463 Rating)
  • Highest rating: 3star
  • Lowest rating: 3star
  • Descriptions: The results strongly indicate that acetazolamide treatment is associated with a substantial increase in the risk of developing aplastic anaemia. Abbreviations:.
  • Source : https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2796.1990.tb00290.x

6.Acetazolamide-Induced Agranulocytosis in a Patient with Pseu…

  • Publish: 19 days ago
  • Rating: 5star(1433 Rating)
  • Highest rating: 5star
  • Lowest rating: 1star
  • Descriptions: Common adverse effects of acetazolamide include paresthesia, fatigue, metallic taste, gastrointestinal upset, loss of appetite, hyperchloremic acidosis, and …
  • Source : https://journals.lww.com/annalsofian/Fulltext/2020/23050/Acetazolamide_Induced_Agranulocytosis_in_a_Patient.43.aspx

7.Hematologic Reactions to Carbonic Anhydrase Inhibitors

  • Publish: 19 days ago
  • Rating: 3star(228 Rating)
  • Highest rating: 5star
  • Lowest rating: 2star
  • Descriptions: Thrombocytopenia and renal lesions associated with acetazolamide (Diamox) … Severe aplastic anemia as a complication of acetazolamide therapy. Can.
  • Source : https://www.ajo.com/article/S0002-9394(14)74987-6/fulltext

8.Side effects of acetazolamide: a systematic review and meta …

  • Publish: 16 days ago
  • Rating: 4star(631 Rating)
  • Highest rating: 4star
  • Lowest rating: 3star
  • Descriptions: Acetazolamide (AZM) is a carbonic anhydrase (CA) inhibitor that has been used … Metabolic acidosis and anaemia associated with dorzolamide in a patient …
  • Source : https://bmjopenrespres.bmj.com/content/7/1/e000557

9.Anemia Common in Idiopathic Intracranial Hypertension Patients

  • Publish: 22 days ago
  • Rating: 3star(1357 Rating)
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  • Lowest rating: 1star
  • Descriptions:
  • Source : https://www.reviewofoptometry.com/article/anemia-common-in-idiopathic-intracranial-hypertension-patients

10.Acetazolamide: Considerations for Systemic Administration

  • Publish: 14 days ago
  • Rating: 1star(1413 Rating)
  • Highest rating: 4star
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  • Descriptions: Rarely, acetazolamide may lead to agranulocytosis or aplastic anemia; these conditions may occur suddenly and are irreversible.1 Therefore, if comanaged with a …
  • Source : https://www.aao.org/eyenet/article/acetazolamide-considerations-systemic-administrati

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